Ozempic, Wegovy, Zepbound, and Mounjaro — are no longer whispered about behind closed doors. Award-winning actors, music stars, athletes, and even billionaire CEOs are speaking publicly about using prescription weight loss drugs, moving the conversation away from judgment and toward honesty about health, self-image, and managing weight in the spotlight.
Here’s a breakdown of stars who’ve opened up about their GLP-1 journeys — what worked, what didn’t, and how the medications affected their lives. Scroll through our gallery to uncover all of the celebrities who’ve gotten real about weight loss drugs.

